165674-44-2

Upstream product

• 133382-26-0 (E)-2-cyanocinnamate of (S)-ethyl lactate 
• 162272-50-6 (1S,6R)-1-Cyano-6-phenyl-3-cyclohexene-1-carboxylic acid 
• 162272-56-2 Methyl (1S,2R)-1-cyano-2-phenyl-1-cyclohexanecarboxylate 
• 162272-48-2 (S)-Ethyl lactate (1S,6R)-1-cyano-6-phenyl-3-cyclohexene-1-carboxylate 
• 165674-38-4 (1S,6R)-methyl 1-cyano-6-phenyl-3-cyclohexene-1-carboxylate 
• 165674-42-0 Methanesulfonic acid (1S,2R)-1-cyano-2-phenyl-cyclohexylmethyl ester 
• 165674-40-8 (1S,2R)-1-hydroxymethyl-2-phenyl-1-cyclohexanecarbonitrile 
• 165674-43-1 (1R,2R)-1-Azidomethyl-2-phenyl-cyclohexanecarbonitrile 

Relevant academic research and scientific papers

Synthesis of a new type of conformationally constrained α,α-disubstituted-β-amino acids and β-lactams in enantiomerically pure form

Optically active cis-, 8a and 8b, and trans-1-aminomethyl-2-phenylcyclohexane-1-carboxylic acids, 9a and 9b, were obtained starting from 1,3-butadiene using Diels-Alder cycloadditions with chiral (E)-2-cyanocinnamates as key steps and following a protocol