1333899-75-4Relevant academic research and scientific papers
Synthesis and biological activities of novel 1,3,4-thiadiazole-containing pyrazole oxime derivatives
Dai, Hong,Li, Gang,Chen, Jia,Shi, Yujun,Ge, Shushan,Fan, Chongguang,He, Haibing
supporting information, p. 3818 - 3821 (2016/07/21)
A new library of 1,3,4-thiadiazole-containing pyrazole oximes was designed and synthesized. Their acaricidal and insecticidal activities were evaluated. Bioassay results indicated that some target compounds exhibited good acaricidal and insecticidal properties. Especially, compound 8m had 80% acaricidal activity against Tetranychus cinnabarinus at the concentration of 50?μg/mL, compound 8f displayed 100% insecticidal activities against Aphis craccivora at the concentration of 50?μg/mL, compounds 8r and 8w showed 100% insecticidal activities against Plutella xylostella at the concentration of 50?μg/mL. Furthermore, compounds 8r (LC50?=?19.61?μg/mL) and 8w (LC50?=?9.78?μg/mL) possessed comparable or even better insecticidal activities than the control Pyridalyl (LC50?=?17.40?μg/mL) against P. xylostella.
Design, synthesis, and antibacterial evaluation of new Schiff's base derivatives bearing nitroimidazole and pyrazole nuclei as potent E. coli FabH inhibitors
Sangani, Chetan B.,Makwana, Jigar A.,Duan, Yong-Tao,Tarpada, Umesh P.,Patel, Yogesh S.,Patel, Ketan B.,Dave, Vivek N.,Zhu, Hai-Liang
, p. 10137 - 10149 (2016/01/12)
New Schiff's base derivatives 5a-j have been synthesized by reaction between 5-aryloxypyrazole-4-carbaldehydes 3a-j and 2-(2-methyl-5-nitro-1Himidazol- 1-yl)acetohydrazide 4 in the presence of nickel (II) nitrate as a catalyst in ethanol at room temperatu
One step synthesis of pyrido[1,2-a]benzimidazole derivatives of aryloxypyrazole and their antimicrobial evaluation
Jardosh, Hardik H.,Sangani, Chetan B.,Patel, Manish P.,Patel, Ranjan G.
, p. 123 - 126 (2013/06/26)
A new series of pyrido[1,2-a]benzimidazole derivatives bearing the aryloxypyrazole nucleus have been synthesized by base-catalyzed cyclocondensation reaction through multi-component reaction (MCR) approach. All the synthesized compounds were investigated
Microwave-assisted synthesis of novel 4H-chromene derivatives bearing phenoxypyrazole and their antimicrobial activity assessment
Sangani, Chetan B.,Shah, Nimesh M.,Patel, Manish P.,Patel, Ranjan G.
, p. 1165 - 1174 (2012/11/13)
A new series of 4H-chromene derivatives 4a-p bearing the 5-phenoxypyrazole nucleus were synthesized under microwave irradiation by the reaction of 5-phenoxypyrazole-4-carbaldehydes 1a-h, malononitrile 2 and compounds 1,3-cyclohexanedione and dimedone (3a
Synthesis and antimicrobial screening of pyrano[3,2-c]chromene derivatives of 1H-pyrazoles
Sangani, Chetan B.,Mungra, Divyesh C.,Patel, Manish P.,Patel, Ranjan G.
, p. 635 - 647 (2012/04/23)
A new series of twenty four derivatives of pyrano[3,2-c]chromene IVa-x bearing 1H-pyrazole were synthesized by a one pot, base-catalyzed cyclocondensation reaction of 1H-pyrazole-4-carbaldehyde Ia-l, malononitrile II and 4-hydroxycoumarin IIIa-b. All the synthesized compounds were characterized by elemental analysis, FT-IR, 1H NMR and 13C NMR spectral data. All the synthesized compounds were screened against six bacterial pathogens, namely B. subtilis, C. tetani, S. pneumoniae, S. typhi, V. cholerae, E. coli and for antifungal activity against two fungal pathogens, A. fumigatus and C. albicans using the broth microdilution MIC method. Some of the compounds were found to be equipotent or more potent than commercial drugs against most of employed strains, as evident from the screening data. Versita Sp. z o.o.
