1333912-05-2

Basic information

• Product Name: 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester
• Synonyms: 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester
• CAS NO: 1333912-05-2
• Molecular Weight: 411.326
• Mol File: 1333912-05-2.mol

Chemical Properties

• CAS DataBase Reference: 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester(1333912-05-2)
• EPA Substance Registry System: 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester(1333912-05-2)

Safety Data

• Hazardous Substances Data: 1333912-05-2(Hazardous Substances Data)

Upstream product

• 1333912-04-1 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic acid methyl ester 
• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 1333911-91-3 5-((tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic acid 
• 3303-84-2 3-(tert-butyloxycarbonylamino)propionic acid 
• 141734-32-9 5-((tert-butoxycarbonyl)amino)-3-oxopentanoic acid methyl ester 

Downstream Products

• 1333912-07-4 5-(di(tert-butoxycarbonyl)amino)-3-methoxypent-2-enoic pentafluorophenol ester 

Relevant articles and documents

Synthesis of the peptide moiety of the jamaicamides

The jamaicamides, isolated from cyanobacterium Lyngbya majuscula in Jamaica, are unique mixed polyketide-peptides that are reported to be blockers of the sodium channels. The peptide moiety contains a pyrrolinone ring and a β-methoxy enone functionality. Herein, we report the stereoselective synthesis of the N-(Boc)2-protected peptide moiety of the jamaicamides by utilizing Meldrum's acid starting from l-alanine and N-Boc-β-alanine.