133407-39-3

Upstream product

• 3393-45-1 5,6-dihydro-pyran-2-one 
• 133407-38-2 (R)-N-(1-phenylethyl)-N-(methoxymethyl)-N-(trimethylsilylmethyl)amine 
• 134139-07-4 (R)-(+)-N-1-phenylethyl-N-(butoxymethyl)trimethylsilylmethylamine 
• 104942-85-0 (R)-(+)-N-1-phenylethyl-N-trimethylsilylmethylamine 

Downstream Products

• 134139-20-1 (3R,4S)-3-propoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 
• 134139-13-2 (3S,4R)-3-propoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 
• 133407-40-6 (3S,4R)-3-ethoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 
• 134139-14-3 (3R,4S)-3-butoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 
• 134139-14-3 (3S,4R)-3-butoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 
• 135821-85-1 (3R,4S)-3-ethoxycarbonyl-1-<(R)-1-phenylethyl>-1-azoniabicyclo<2.2.1>heptane bromide 

Relevant academic research and scientific papers

Novel antimuscarinic antidepressant-like compounds with reduced effects on cognition

The cholinergic nervous system has been implicated in mood disorders, evident in the fast-onset antidepressant effects of scopolamine, a potent muscarinic antagonist, in clinical studies. One prominent disadvantage of the use of scopolamine in the treatme

Chiral synthesis for producing 1-azabicyclo[2.2.1] heptane-3-carboxylates

A process for preparing substantially pure enantiomers of formula (I) STR1 where the * represents a chiral center, x is 0 or 1, in exo-, endo- or a mixture of exo- and endo- forms; and R is hydrogen, alkyl or aralkyl, via diastereomers of formula (IIA) or

A Synthesis of 1-Azabicycloheptane-3-carboxylic Acid Esters in Enantiomerically Pure Form

A novel synthesis of ethyl 1-azabicycloheptane-3-carboxylate via 1-benzylperhydropyranopyrrol-4-one and 1-benzyl-3-(2-bromoethyl)-4-ethoxycarbonylpyrrolidinium bromide is described.Modification of the method, by incorporation of a chiral substituted benzyl group on the nitrogen atom, has led to the first reported process for the preparation of these esters in enantiomerically pure form.The absolute configuration of the bicyclic esters was deduced by X-ray crystallography of an intermediate, 2-perhydropyranopyrrole-4-one.