133415-15-3

Upstream product

• 32803-73-9 methyl 3-phenyl-3-chloro-2-ketopropionate 
• 62-55-5 thioacetamide 
• 108-86-1 bromobenzene 
• 6436-60-8 methyl 2-methyl-1,3-thiazole-4-carboxylate 
• 35272-15-2 2-methylthiazole-4-carboxylic acid 
• 100-52-7 benzaldehyde 

Downstream Products

• 139156-69-7 2-methyl-5-phenylthiazolecarbohydrazide 
• 13743-09-4 2-methyl-5-phenyl-1,3-thiazole-4-carboxylic acid 
• 1117693-63-6 2-methyl-5-phenyl-thiazole-4-carboxylic acid {(RS)-2-[(benzofuran-4-carbonyl)-amino]-1-cyclopropyl-ethyl}-methyl-amide 
• 139521-46-3 2-[N'-(2-Methyl-5-phenyl-thiazole-4-carbonyl)-hydrazino]-5-phenyl-thiazole-4-carboxylic acid isobutyl ester 
• 139156-77-7 2-[N'-(2-Methyl-5-phenyl-thiazole-4-carbonyl)-hydrazino]-5-phenyl-thiazole-4-carboxylic acid propyl ester 
• 139156-79-9 2-[N'-(2-Methyl-5-phenyl-thiazole-4-carbonyl)-hydrazino]-5-phenyl-thiazole-4-carboxylic acid diethylamide 
• 139156-78-8 2-[N'-(2-Methyl-5-phenyl-thiazole-4-carbonyl)-hydrazino]-5-phenyl-thiazole-4-carboxylic acid isopropyl ester 
• 139156-76-6 2-[N'-(2-Methyl-5-phenyl-thiazole-4-carbonyl)-hydrazino]-5-phenyl-thiazole-4-carboxylic acid ethyl ester 
• 139156-75-5 methyl 2-<2'-(2''-methyl-5''-phenylthiazolecarbonyl)hydrazo>-5-phenylthiazolecarboxylate 
• 139156-80-2 2-methyl-5-phenylthiazoline-4-carboxylic acid N-(3'-phenyl-4'-oxo-1',3'-thiazolidin-2'-ylidene)hydrazide 
• 139156-73-3 2-methyl-5-phenylthiazolecarboxylic acid 4-phenylthiosemicarbazide 
• 139156-71-1 2-methyl-5-phenylthiazolecarboxylic acid thiosemicarbazide 
• 797030-55-8 2-methylindeno[2,1-d]thiazol-4-one 

Relevant academic research and scientific papers

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to thiazolidine derivatives of the formula (I) wherein A, B, and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to their use as medicaments, especially

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R2, R3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.

Mechanism selection for regiocontrol in base-assisted, palladium-catalysed direct C-H coupling with halides: First approach for oxazole- and thiazole-4-carboxylates

Both base-assisted non-concerted metallation-deprotonation (nCMD) and concerted metallation-deprotonation (CMD) have been identified as two potent operating mechanisms in palladium-catalysed direct C-H coupling of oxazole and thiazole-4-carboxylate esters

THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to thiazolidine derivatives of the formula (I) wherein A, B, and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to their use as medicaments, especially

THIAZOLIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to novel thiazolidine derivatives of the formula (I) wherein A and R1 are as described in the description and their use as medicaments, especially as orexin receptor antagonists.

AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to novel azetidine compounds of formula (I), wherein R1, R2, and X are as described in the description and their use as orexin receptor antagonists.

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES

The invention relates to novel 2-aza-bicyclo[2.2.1]heptane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as m