1334296-01-3Relevant academic research and scientific papers
A simple efficient sequential one-pot intermolecular aza-Michael addition and intramolecular Buchwald-Hartwig α-arylation of amines: Synthesis of functionalized tetrahydroisoquinolines
Reddy, Alavala Gopi Krishna,Satyanarayana, Gedu
experimental part, p. 8003 - 8010 (2012/09/25)
An efficient one-pot sequential intermolecular aza-Michael addition and Pd-catalyzed intramolecular Buchwald-Hartwig α-arylation of secondary amines have been investigated, for the synthesis of tetrahydroisoquinolines. This method is simple and furnished
Palladium-mediated intramolecular Buchwald-Hartwig α-arylation of β-amino esters: Synthesis of functionalized tetrahydroisoquinolines
Reddy, A. Gopi Krishna,Krishna,Satyanarayana
, p. 1756 - 1760 (2011/09/16)
A concise and efficient three-step strategy for the synthesis of functionalized 1,2,3,4-tetrahydroisoquinolines based on an intramolecular Buchwald-Hartwig α-arylation of β-amino esters is described. The synthesis presented is operationally simple and is amenable for the synthesis of a number of analogues. Georg Thieme Verlag Stuttgart · New York.
