13345-08-9

Basic information

• Product Name: 6-n-propyluracil
• Synonyms: 6-n-propyluracil
• CAS NO: 13345-08-9
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.17
• Mol File: 13345-08-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.126g/cm³
• Refractive Index: 1.481
• CAS DataBase Reference: 6-n-propyluracil(CAS DataBase Reference)
• NIST Chemistry Reference: 6-n-propyluracil(13345-08-9)
• EPA Substance Registry System: 6-n-propyluracil(13345-08-9)

Safety Data

• Hazardous Substances Data: 13345-08-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H10N2O2/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

Upstream product

• 51-52-5 propylthiouracil 
• 3249-68-1 ethyl butyroyl acetate 
• 57-13-6 urea 

Downstream Products

• 28267-45-0 1,3-dimethyl-6-n-propyluracil 
• 73576-45-1 4-(2,4-Diamino-6-propyl-pyrimidin-5-ylmethyl)-2,6-dimethoxy-phenol 
• 73576-25-7 6-Propyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4-diamine 
• 1423655-62-2 2-[(5-bromo-2-chloro-6-propylpyrimidin-4-yl)sulfanyl]aniline 
• 1423655-72-4 2-(4-phenylpiperazin-1-yl)-4-propyl-pyrimido[4,5-b][1,4]benzothiazine 
• 1373331-52-2 1-(7-chloro-1-phenyl-5-propyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-yl)-2-phenyldiazene 
• 1373331-60-2 1-(7-(4-methylpiperazin-1-yl)-1-phenyl-5-propyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-yl)-2-phenyldiazene 
• 1373331-59-9 1-(7-(morpholin-4-yl)-1-phenyl-5-propyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-yl)-2-phenyldiazene 
• 1373331-58-8 2-phenyl-1-(1-phenyl-7-(piperidin-1-yl)-5-propyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-yl)diazene 
• 178425-37-1 1-[(2R,4S,5S)-4-Azido-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-propyl-1H-pyrimidine-2,4-dione 
• 178425-36-0 1-[(2S,4S,5S)-4-Azido-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-propyl-1H-pyrimidine-2,4-dione 
• 917567-70-5 6-propyl-3-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)(1H)pyrimidine-2,4-dione 
• 89938-07-8 2,6-dichloro-4-n-propyl-pyrimidine 

Relevant articles and documents

Analytical studies on thiouracils. II. Dissociation constants of thiouracils and their reactions with hydrogen peroxide (author's transl)

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Synthesis of modified uracil and cytosine nucleobases using a microwave-assisted method

Modified nucleobases and nucleic acids have found many biological and pharmaceutical applications. Here we report a microwave-directed synthesis of a variety of modified uracil and cytosine nucleobases with high yields under solvent-free conditions. The reaction yields were further improved by addition of Lewis acid. The crystal structures of 5-isopropyl-6-methyluracil and 6-phenyluracil were also determined.

Synthesis of an AZT-HEPT hybrid and homologous AzddU derivatives

3′-Azido-2′,3′-dideoxyuridines 6 and their corresponding α anomers 5 were syrthesizes by condensation of silylated 6-alkyl and 5,6-dialkyl substituted uracils 2 with methyl 3-azido-5-O-tert-butyldiphenylsilyl-2,3-dideoxy-α,β-D-erythro- pentofuranoside (4). Compounds 5 and 6 were treated with tetrabutylammonium fluoride to obtain the deprotected nucleosides 7 and 8, respectively. Acta Chemica Scandinavica 1996.