1334712-98-9Relevant academic research and scientific papers
NEW COMPOUNDS
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Paragraph 0131; 0132, (2016/02/16)
The compound of formula (I) are inhibitors of SSAO activity (Formula (I)) wherein the terms Y, Z, W, R1 and R2 are defined in the claims.
NEW COMPOUNDS
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, (2015/10/06)
The present invention provides certain compounds according to formula (I) which are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the specification.
IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS
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Page/Page column 61, (2014/09/29)
The compounds of formula (I) are inhibitors of semicarbazide- sensitive amine oxidase (SSAO) activity useful in the treatment of inflammation, an inflammatory disease, an immune or an autoimmune disorder, or inhibition of tumour growth.
NEW COMPOUNDS
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Paragraph 0174; 0175, (2014/09/29)
The present invention relates to compounds which are inhibitors of SSAO activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment or prevention of medical conditions w
New Enzyme Inhibitor Compounds
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Paragraph 0205; 0206, (2013/05/08)
Disclosed are compounds which inhibit SSAO enzyme activity. Also disclosed are pharmaceutical compositions comprising these compounds and the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumour growth.
New aromatase inhibitors from the 3-pyridyl arylether and 1-aryl pyrrolo[2,3-c]pyridine series
Stauffer, Frédéric,Furet, Pascal,Floersheimer, Andreas,Lang, Marc
experimental part, p. 1860 - 1863 (2012/04/17)
Aromatase inhibition is the new standard of care for estrogen receptor positive breast cancer and has also potential for treatment of other diseases such as endometriosis. Simple and readily available 3-pyridyl arylethers and 1-aryl pyrrolo[2,3-c]pyridines recapitulating the key pharmacophore elements of Letrozole (1) are described and their structure-activity relationships are discussed. Potent and ligand efficient leads such as compound 23 (IC 50 = 59 nM on aromatase) have been identified.
NEW ENZYME INHIBITOR COMPOUNDS
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Page/Page column 39-40, (2011/10/10)
Compounds of formula (I) are inhibitors of Semicarbazide-sensitive amine oxidase wherein R1, A, X and R2 are as defined in the claims.
