1334725-14-2

Basic information

• Product Name: C₃₃H₃₇O₈P
• Synonyms: C₃₃H₃₇O₈P
• CAS NO: 1334725-14-2
• Molecular Weight: 592.626
• Mol File: 1334725-14-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₃H₃₇O₈P(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₃H₃₇O₈P(1334725-14-2)
• EPA Substance Registry System: C₃₃H₃₇O₈P(1334725-14-2)

Safety Data

• Hazardous Substances Data: 1334725-14-2(Hazardous Substances Data)

Upstream product

• 1221156-99-5 3'-benzyloxy-4'-ethoxy-3,4,5-trimethoxy stilbene 
• 52987-93-6 2-(4-ethoxy-3-methoxyphenyl)-1,3-dioxolane 
• 120-25-2 4-ethoxy-3-methoxybenzaldehyde 
• 26691-25-8 3-(benzyloxy)-4-ethoxybenzaldehyde 
• 1623-08-1 phosphoric acid dibenzyl ester 
• 1221157-00-1 3'-hydroxyl-4'-ethoxy-3,4,5-trimethoxy diphenylethane 
• 2539-53-9 4-ethoxy-3-hydroxybenzaldehyde 
• 121-33-5 vanillin 

Relevant articles and documents

ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF

The invention discloses an ethoxydiphenylethane derivative and a synthetic method and uses thereof 4' position of phenylethane B aromatic ring is chemically modified by ethoxy and hydroxy at position 3' thereof is simultaneously modified to water soluble prodrug such as phosphate, and similarly, amino acid side chain is introduced to amino at position 3' to form amino acid amide water soluble prodrug having the structure shown as formula (I) the ethoxydiphenylethane derivative and the prodrug thereof include strong tubulin aggregation inhibiting ability and obvious target damage effect for tumor vessels, selectively cause dysfunction and structural damage of tumor vessels and induce apoptosis of vascular endothelial cells in order to play the role of killing tumor cells or inhibiting tumor metastasis in case that the tumor cells are free from the support of nutrition and oxygen.