1334783-14-0

Basic information

• Product Name: 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile
• Synonyms: 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile
• CAS NO: 1334783-14-0
• Molecular Weight: 507.635
• Mol File: 1334783-14-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile(1334783-14-0)
• EPA Substance Registry System: 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile(1334783-14-0)

Safety Data

• Hazardous Substances Data: 1334783-14-0(Hazardous Substances Data)

Upstream product

• 52786-67-1 (2-cyano-4-methoxyphenyl)acetic acid 
• 1261620-25-0 (2-bromo-4-methoxy-phenyl)-acetic acid 
• 198630-93-2 methyl 2-(2-bromo-4-methoxyphenyl)acetate 
• 66916-99-2 2-(2-bromo-4-(methoxy)phenyl)acetic acid 

Relevant articles and documents

Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonists

Several polar heteroaromatic acetic acids and their piperidine amides were synthesized and evaluated as ghrelin or type 1a growth hormone secretagogue receptor (GHS-R1a) inverse agonists. Efforts to improve pharmacokinetic and safety profile was achieved