13349-96-7

Upstream product

• 59693-90-2 n-hexyl 4-methoxyphenyl sulfide 
• 763-29-1 2-Methyl-1-pentene 
• 637-89-8 4-sulfanylphenol 
• 497-19-8 sodium carbonate 
• 106-41-2 4-bromo-phenol 
• 111-31-9 Hexanethiol 
• 123-30-8 4-amino-phenol 
• 111-25-1 1-bromo-hexane 
• 696-63-9 4-Methoxybenzenethiol 
• 22487-02-1 sodium n-hexylmercaptide 
• 156-43-4 4-Ethoxyaniline 

Relevant academic research and scientific papers

Mono- And Dinuclear α-Diimine Nickel(II) and Palladium(II) Complexes in C-S Cross-Coupling

The usefulness of transition metal catalytic systems in C-S cross-coupling reactions is significantly reduced by air and moisture sensitivity, as well as harsh reaction conditions. Herein, we report four highly air- and moisture-stable well-defined mononuclear and bridged dinuclear α-diimine Ni(II) and Pd(II) complexes for C-S cross-coupling. Various ligand frameworks, including acenaphthene- and iminopyridine-based ligands, were employed, and the resulting steric properties of the catalysts were evaluated and correlated with reaction outcomes. Under aerobic conditions and low temperatures, both Ni and Pd systems exhibited broader substrate scope and functional group tolerance than previously reported catalysts. Over 40 compounds were synthesized from thiols containing alkyl, benzyl, and heteroaryl groups. Also, pharmaceutically active heteroaryl moieties are incorporated from thiol and halide sources. Notably, the bridged dinuclear five-coordinate Ni complex has outperformed the remaining three mono four- or six-coordinate complexes by giving almost quantitative yields across a broad substrate scope.

Alkyl- and Arylthiodediazoniations of Dry Arenediazonium o-Benzenedisulfonimides. Efficient and Safe Modifications of the Stadler and Ziegler Reactions to Prepare Alkyl Aryl and Diaryl Sulfides

The reaction between dry arenediazonium o-benzenedisulfonimides 1 and sodium thiolates in anhydrous methanol represents an efficient and safe procedure, of general validity, for the preparation of unfunctionalized or variously functionalized alkyl aryl and diaryl sulfides. As a rule, the reaction temperature was maintained at 0-5°C for the alkylthiodediazoniations and at room temperature (20-25°C) for the arylthiodediazoniations. The sulfide yields are generally high; of the 63 considered examples, 43 gave yields greater than 80% and 13 were between 70% and 80%. Lower yields were obtained only when sterically hindered diazonium salts or thiols were used. A good amount of the o-benzenedisulfonimide (8) was always recovered from the reactions and could be reused to prepare salts 1. The copious experimental data collected in homogeneous conditions have offered several starting points for the study of the mechanism of these reactions.

Mercapto phenolic and alkylthio phenolic antioxidants

2-Mercapto phenol and/or 4-mercapto phenol are reacted with a compound selected from olefins, alcohols, and organic halides for example, styrene and isobutylene, to form (hydrocarbyl) thio phenolic antioxidants such as 2,6-di-tert. butyl-4-(tert.butylthio) phenol and 2,6-di(α-phenylethyl)-4-(α-phenylethylthio)phenol.