133496-79-4Relevant academic research and scientific papers
Lithiation and Isomerization of Allylic Amines as a General Route to Enamines and Their Carbonyl Derivatives
Eisch, John J.,Shah, Jamshed H.
, p. 2955 - 2957 (2007/10/02)
lithium, readily prepared by the lithiation of allyldiphenylamine with n-butyllithium in THF, undergoes alkylation either with organic halides or with carbonyl or azomethine derivatives to yield enamines, which can be converted by protons or other electrophiles into aldehydes or into five-membered heterocycles; lithiation of such allyldiarylamines with other reagents leads principally to isomerisation to enamines (with lithium diisopropylamide) or to carbenoid intermediates (tert-butyllithium and potassium tert-butoxide).
