1335099-97-2Relevant academic research and scientific papers
Pantolactams as androgen receptor antagonists for the topical suppression of sebum production
Sexton, Karen E.,Barrett, Stephen,Bridgwood, Katy,Carroll, Matthew,Dettling, Danielle,Du, Daniel,Fakhoury, Stephen,Fedij, Victor,Hu, Lain-Yen,Kostlan, Catherine,Pocalyko, David,Raheja, Neil,Smith, Yvonne,Shanmugasundaram, Veerabahu,Wade, Kimberly
scheme or table, p. 5230 - 5233 (2011/10/09)
A series of pantolactam based compounds were identified as potent antagonists for the androgen receptor (AR). Those that possessed properties suitable for topical delivery were evaluated in the validated Hamster Ear Model. Several compounds were found to
