914100-91-7

Upstream product

• 878209-30-4 (+/-)-4-(4,4-dimethyl-2-oxotetrahydrofuran-3-yloxy)-2-(trifluoromethyl)benzonitrile 
• 914100-92-8 2-(4-cyano-3-trifluoromethyl-phenoxy)-N-2,4-dimethoxy-benzyl-4-hydroxy-3,3-dimethyl-butyramide 
• 914100-93-9 methanesulfonic acid 3-(4-cyano-3-trifluoromethyl-phenoxy)-3-(2,4-dimethoxy-benzylcarbamoyl)-2,2-dimethyl-propyl ester 
• 194853-86-6 4-fluoro-2-(trifluoromethyl)benzonitrile 
• 79-50-5 pantolactone 

Downstream Products

• 1335099-99-4 C₁₇H₁₉F₃N₂O₂S 
• 1335099-98-3 C₁₇H₁₉F₃N₂O₃ 
• 1335099-96-1 C₂₀H₂₅F₃N₂O₂ 
• 1335100-03-2 C₁₈H₂₀F₃N₃O₃ 
• 1335100-00-9 C₁₇H₁₉F₃N₂O₃ 
• 1335099-97-2 C₁₆H₁₇F₃N₂O₃ 
• 1335100-01-0 C₁₇H₁₇F₃N₂O₄ 
• 1335099-92-7 C₁₅H₁₅F₃N₂O₂ 
• 1335099-93-8 C₂₀H₂₅F₃N₂O₂ 

Relevant academic research and scientific papers

Compound with androgen receptor (AR) degradation activity

The invention provides a type of compound with androgen receptor (AR) degradation activity, and specifically provides a compound as shown in the following formula I: (please see the specification forthe formula), wherein all groups are as defined in the s

Pantolactams as androgen receptor antagonists for the topical suppression of sebum production

A series of pantolactam based compounds were identified as potent antagonists for the androgen receptor (AR). Those that possessed properties suitable for topical delivery were evaluated in the validated Hamster Ear Model. Several compounds were found to

Androgen modulators

The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.