914100-93-9

Upstream product

• 914100-92-8 2-(4-cyano-3-trifluoromethyl-phenoxy)-N-2,4-dimethoxy-benzyl-4-hydroxy-3,3-dimethyl-butyramide 
• 124-63-0 methanesulfonyl chloride 
• 2393-23-9 4-methoxy-benzylamine 
• 878209-30-4 (+/-)-4-(4,4-dimethyl-2-oxotetrahydrofuran-3-yloxy)-2-(trifluoromethyl)benzonitrile 

Downstream Products

• 1335099-93-8 C₂₀H₂₅F₃N₂O₂ 
• 1335099-96-1 C₂₀H₂₅F₃N₂O₂ 
• 1335099-97-2 C₁₆H₁₇F₃N₂O₃ 
• 1335099-98-3 C₁₇H₁₉F₃N₂O₃ 
• 1335099-99-4 C₁₇H₁₉F₃N₂O₂S 
• 1335100-00-9 C₁₇H₁₉F₃N₂O₃ 
• 1335100-01-0 C₁₇H₁₇F₃N₂O₄ 
• 1335100-03-2 C₁₈H₂₀F₃N₃O₃ 
• 914100-91-7 (+/-)-4-(4,4-dimethyl-2-oxopyrrolidin-3-yloxy)-2-(trifluoromethyl)benzonitrile 
• 1335099-92-7 C₁₅H₁₅F₃N₂O₂ 

Relevant academic research and scientific papers

Pantolactams as androgen receptor antagonists for the topical suppression of sebum production

A series of pantolactam based compounds were identified as potent antagonists for the androgen receptor (AR). Those that possessed properties suitable for topical delivery were evaluated in the validated Hamster Ear Model. Several compounds were found to

Androgen modulators

The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.