1335200-83-3Relevant academic research and scientific papers
An improved stereoselective total synthesis of (R)-rugulactone
Goswami, Abhishek,Saikia, Partha Pratim,Saikia, Bishwajit,Chaturvedi, Devdutt,Barua, Nabin C.
, p. 5133 - 5135 (2011)
A novel route for the stereoselective total synthesis of (R)-rugulactone 1 has been developed, starting from substituted epoxide 4 and 3- phenylpropionaldehyde 5 employing Julia-Kocienski olefination as a key step to construct E-configured α,β-unsaturated keto-group. The overall yield of the synthesized rugulactone is 19.94% and is better than the reported methods.
