133523-45-2Relevant articles and documents
On the Remarkable Propensity for Carbon-Carbon Bond Cleavage Reactions in the C8-C10 Region of FK-506
Fisher, Matthew J.,Chow, Ken,Villalobos, Anabella,Danishefsky, Samuel J.
, p. 2900 - 2907 (2007/10/02)
It has been deduced from a series of transformations that formation of a tetrahedral intermediate at C9 in FK-506 occasions fragmentation of the C9-C10 bond by a retro-Claisen-like pathway or the C9-C8 bond by a benzilic acid type rearrangement.Reduction