133535-66-7

Basic information

• Product Name: 5-ethyl-1-(phenylmethyl)-2-pyrrolidinone
• Synonyms: 5-ethyl-1-(phenylmethyl)-2-pyrrolidinone
• CAS NO: 133535-66-7
• Molecular Weight: 203.284
• Mol File: 133535-66-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-ethyl-1-(phenylmethyl)-2-pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethyl-1-(phenylmethyl)-2-pyrrolidinone(133535-66-7)
• EPA Substance Registry System: 5-ethyl-1-(phenylmethyl)-2-pyrrolidinone(133535-66-7)

Safety Data

• Hazardous Substances Data: 133535-66-7(Hazardous Substances Data)

Upstream product

• 71-43-2 benzene 
• 10444-23-2 4-(hydroxymethyl)hexanenitrile 
• 10444-17-4 ethyl 4-cyano-2-ethylbutanoate 
• 10444-12-9 diethyl 2-(2-cyanoethyl)-2-ethylmalonate 
• 82259-07-2 5-ethoxy-1-(phenylmethyl)-2-pyrrolidinone 
• 41194-02-9 1-benzyl-5-hydroxypyrrolidin-2-one 
• 2142-06-5 1-(phenylmethyl)-2,5-pyrrolidinedione 
• 2386-64-3 ethylmagnesium chloride 
• 133535-61-2 1-(phenylmethyl)-5-(phenylsulphonyl)-2-pyrrolidinone 

Relevant articles and documents

Schmidt Reaction of ω-Azido Valeryl Chlorides Followed by Intermolecular Trapping of the Rearrangement Ions: Synthesis of Assoanine and Related Pyrrolophenanthridine Alkaloids

The Schmidt reaction of ω-azido valeryl chlorides in the presence of an additional nucleophile was explored. The arenes, alcohols, and amines were demonstrated as the intermolecular trapping reagents for isocyanate ion and N-acyliminium ion from the Schmidt rearrangement, affording the corresponding products with moderate to excellent yields. Two 2-oxoindoles from the reaction were successfully converted into four natural alkaloids, namely, assoanine, anhydrolycorine, oxoassoanine, and anhydrolycorinone.