133545-35-4Relevant academic research and scientific papers
Catalyst-Free Synthesis of Aryl Diamines via a Three-Step Reaction Process
Bulut, Safak,Queen, Wendy L.
, p. 3806 - 3818 (2018/04/14)
The formation of C-N bonds with aryl amines is one of the most widely studied reactions in organic chemistry. Despite this, it is still highly challenging, often requiring expensive, precious metal-based catalysts. Here we report an easy catalyst-free methodology for constructing C-N bonds. The method, which proceeds via the in situ formation of closed ring amidinium ions, allows the preparation of a series of symmetrical and/or unsymmetrical aryl diamines in notably high yields (82-98%) and purity and with a variety of different substituents. The methodology is shown successful for the preparation of aryl diamines having para- and/or meta-substituted carboxyl, nitro, bromo, methoxy, or methyl groups. This green synthetic pathway, which is catalyst free, requires only three steps, and proceeds without the need for purification. Further, it is a new sustainable, economically viable method to achieve an otherwise challenging bond formation.
Bis-4-aminobenzamidines: Versatile, fluorogenic A/T-selective dsDNA binders
Vazquez, Olalla,Sanchez, Mateo I.,Martinez-Costas, Jose,Vazquez, M. Eugenlo,Mascarenas, Jose L.
supporting information; experimental part, p. 216 - 219 (2010/03/30)
(Figure presented) N1, N3-Bls(4-amldlnophenyl) propane-1, 3-dlamlne (BAPPA, R = H) Is a blsamlnobenzamldlne fluorogenlc derivative that displays a large Increase In Its emission fluorescence when bound to the minor groove of specific A/T DNA sites (Kd for an AATT site ～ 79 ± 6 nM). Moreover, the structural characteristics of BAPPA allow the easy Introduction of functional groups that protrude out of the DNA surface.
Double secondary para-phenylenediamine compounds, dye compositions comprising same, and dyeing process using the compositions
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Page/Page column 6-7, (2008/06/13)
The present disclosure relates to double secondary para-phenylenediamine dye compounds. The present disclosure further relates to a dye composition comprising at least one double secondary para-phenylenediamine compound, a process for dyeing keratin fiber
