133641-63-1Relevant academic research and scientific papers
Facile palladium-mediated substitution of chlorine in 2-chloroquinolines
Ciufolini, Marco A.,Mitchell, James W.,Roschangar, Frank
, p. 8281 - 8284 (1996)
Unlike ordinary aryl chlorides, the title heterocycles participate readily in Castro-Stephens, Stille, Suzuki, and carbonylation reactions under the catalytic influence of Pd(0).
NH4I-mediated sp3 C-H cross-dehydrogenative coupling of benzylamines with 2-methylquinoline for the synthesis of E-2-styrylquinolines
Huang, Bin,Li, Xue,Liao, WeiBo,Wang, JiangWei,Zhang, YuanYuan
, p. 903 - 910 (2021/07/17)
Without any metal catalyst, a simple and efficient method for the synthesis of E-2-styrylquinolines through sp3 C-H cross-dehydrogenative coupling of benzylamines with 2-methylquinolines mediated by NH4I under air is successfully developed. The oxidative olefination proceeded through deamination and sp3 C–H bond activation. A plausible mechanism is proposed for the construction of E-2-styrylquinolines.
Iodine-Catalyzed Direct C-H Alkenylation of Azaheterocycle N-Oxides with Alkenes
Zhang, Zhenhao,Pi, Chao,Tong, Heng,Cui, Xiuling,Wu, Yangjie
supporting information, p. 440 - 443 (2017/02/10)
An efficient and regioselective alkenylation of azaheterocycle N-oxides with alkenes catalyzed by iodine under metal- and external oxidant-free reaction conditions has been developed. A variety of (E)-2-styrylazaheterocycles have been produced in moderate
