1337541-79-3

Basic information

• Product Name: 4,4,5,5-tetramethyl-2-(4-phenethylphenyl)-1,3,2-dioxaborolane
• Synonyms: 4,4,5,5-tetramethyl-2-(4-phenethylphenyl)-1,3,2-dioxaborolane
• CAS NO: 1337541-79-3
• Molecular Weight: 308.228
• Mol File: 1337541-79-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4,4,5,5-tetramethyl-2-(4-phenethylphenyl)-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,5,5-tetramethyl-2-(4-phenethylphenyl)-1,3,2-dioxaborolane(1337541-79-3)
• EPA Substance Registry System: 4,4,5,5-tetramethyl-2-(4-phenethylphenyl)-1,3,2-dioxaborolane(1337541-79-3)

Safety Data

• Hazardous Substances Data: 1337541-79-3(Hazardous Substances Data)

Upstream product

• 1190376-20-5 4,4,5,5-tetramethyl-2-[4-(2-phenylethynyl)phenyl]-1,3,2-dioxaborolane 
• 943858-44-4 4,4,5,5-tetramethyl-2-[4-[(1E)-2-phenylethenyl]phenyl]-1,3,2-dioxaborolane 
• 2156-04-9 4-Vinylphenylboronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 100-42-5 styrene 
• 103-63-9 1-phenyl-2-bromoethane 
• 73852-88-7 2-(4-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 64-18-6 formic acid 
• 114-84-1 phenylpropionic acid sodium salt 

Downstream Products

• 1422172-80-2 6-(4-phenethylphenyl)pyridin-3-amine 
• 1422172-81-3 3-methyl-N-(6-(4-phenethylphenyl)pyridin-3-yl)butanamide 
• 1422172-79-9 4-nitro-4'-phenethylbiphenyl 
• 1422172-97-1 5-nitro-2-(4-phenethylphenyl)pyridine 

Relevant articles and documents

Nickel-Catalyzed Regiodivergent Reductive Hydroarylation of Styrenes

We report a ligand-controlled nickel-catalyzed reductive hydroarylation of styrenes with predictable and controllable regioselectivity. With a diamine ligand, the reaction produces selective linear hydroarylation products. Alternatively, with a chiral PyrOx ligand, branch-selective enantioenriched 1,1-diarylalkane products are obtained. Preliminary mechanistic results are consistent with a reductive Heck process.

Olefin cross-metathesis/Suzuki-Miyaura reactions on vinylphenylboronic acid pinacol esters

A series of alkenyl phenylboronic acid pinacol esters has been synthesized via an olefin cross-metathesis reaction of vinylphenylboronic acid pinacol ester derivatives. After catalytic hydrogenation, the resulting boronates were coupled via a microwave-mediated Suzuki-Miyaura reaction to afford a library of biarylethyl aryl and biarylethyl cycloalkyl derivatives. A complementary reaction sequence involved an initial Suzuki-Miyaura coupling.

Facile regio- and stereoselective hydrometalation of alkynes with a combination of carboxylic acids and group 10 transition metal complexes: Selective hydrogenation of alkynes with formic acid

A facile, highly stereo- and regioselective hydrometalation of alkynes generating alkenylmetal complex is disclosed for the first time from a reaction of alkyne, carboxylic acid, and a zerovalent group 10 transition metal complex M(PEt3)4 (M = Ni, Pd, Pt). A mechanistic study showed that the hydrometalation does not proceed via the reaction of alkyne with a hydridometal generated by the protonation of a carboxylic acid with Pt(PEt 3)4, but proceeds via a reaction of an alkyne coordinate metal complex with the acid. This finding clarifies the long proposed reaction mechanism that operates via the generation of an alkenylpalladium intermediate and subsequent transformation of this complex in a variety of reactions catalyzed by a combination of Bronsted acid and Pd(0) complex. This finding also leads to the disclosure of an unprecedented reduction of alkynes with formic acid that can selectively produce cis-, trans-alkenes and alkanes by slightly tuning the conditions.