1337541-83-9

Upstream product

• 1337541-80-6 ethyl (4-(hex-1-yn-1-yl)phenyl)carbamate 
• 64-19-7 acetic acid 
• 77774-39-1 1-(N-ethoxycarbonylamino)-4-iodobenzene 
• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 1370552-58-1 ethyl (4-(3-butyl-4-iodo-5-(p-tolyl)furan-2-yl)phenyl)carbamate 
• 1370552-80-9 (E)-1-(4-((ethoxycarbonyl)amino)phenyl)-2-(p-tolylethynyl)hex-1-en-1-yl acetate 

Relevant academic research and scientific papers

Multisubstituted furan formation from (Z)- or (E)-enynyl acetates: Tandem reactions accelerated by electron-donating groups on aromatic rings

Multisubstituted furans were readily prepared from (Z)- or (E)-conjugated enynyl acetates with NXS under metal-free conditions at room temperature via the same haloallenyl ketone intermediates. This tandem haloallenyl ketone formation-furan formation reaction sequence was accelerated by electron-donating groups on the aromatic rings.

Regio- and stereoselective multisubstituted enol ester synthesis

Regio- and stereoselective cohalogenation of alkynes with NXS (X = Br, I) was achieved, and the stereoselectivity of the resulting alkenes was dependent on the substituent on the alkyne. Cohalogenation and successive cross-coupling gave multisubstituted e