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[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetic acid hydrazide is a hydrazide derivative featuring a quinazolin-4-one core structure and a sulfanyl-acetic acid moiety. This chemical compound is recognized for its potential as a drug candidate due to its diverse pharmacological properties, which include anticancer and antimicrobial activities.

133764-45-1

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133764-45-1 Usage

Uses

Used in Pharmaceutical Industry:
[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetic acid hydrazide is used as a potential drug candidate for its demonstrated anticancer and antimicrobial activities. [3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetic acid hydrazide's unique structure and properties make it a promising agent for further investigation and development in the field of pharmaceuticals.
Used in Cancer Therapy:
In cancer therapy, [3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetic acid hydrazide is utilized for its potential to target and treat various types of cancer. Its pharmacological properties allow it to be a candidate for further research into its efficacy and safety in combating cancer cells.
Used as an Antibacterial and Antifungal Agent:
[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetic acid hydrazide is also used as a potential antibacterial and antifungal agent, showcasing its versatility in the medical field. Its ability to combat bacterial and fungal infections makes it a valuable candidate for the development of new treatments and therapies to address the growing concerns of antibiotic resistance and the need for novel antifungal medications.

Check Digit Verification of cas no

The CAS Registry Mumber 133764-45-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,7,6 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 133764-45:
(8*1)+(7*3)+(6*3)+(5*7)+(4*6)+(3*4)+(2*4)+(1*5)=131
131 % 10 = 1
So 133764-45-1 is a valid CAS Registry Number.

133764-45-1Relevant academic research and scientific papers

Experimental and theoretical spectroscopic studies, HOMO-LUMO, NBO analyses and thione-thiol tautomerism of a new hybrid of 1,3,4-oxadiazole-thione with quinazolin-4-one

Soliman, Saied M.,Hagar, Mohamed,Ibid, Farahate,El Ashry, El Sayed H.

, p. 270 - 279 (2015)

Abstract The hybrid 3-(4-chlorophenyl)-2-[(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)methylthio]quinazolin-4(3H)-one has been synthesized and characterized using elemental analysis, FTIR and NMR spectroscopy. The thione-thiol tautomeric equilibria has bee

Synthesis, molecular structure and spectroscopic studies of some new quinazolin-4(3H)-one derivatives; An account on the N- versus S-Alkylation

Hagar, Mohamed,Soliman, Saied M.,Ibid, Farahate,El Ashry, El Sayed H.

, p. 667 - 679 (2016/01/09)

A new series of N- and S-alkylated products of 3-aryl-1H,3H-quinazolin-2,4-dione and 3-aryl-2-mercapto-3H-quinazolin-4-one, respectively, were prepared in good yields via efficient nucleophilic substitution reaction of the SH and NH substrates with methyl

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