1337864-01-3Relevant articles and documents
Using boronolectin in MALDI-MS imaging for the histological analysis of cancer tissue expressing the sialyl Lewis X antigen
Dai, Chaofeng,Cazares, Lisa H.,Wang, Lifang,Chu, Yong,Wang, Siming L.,Troyer, Dean A.,Semmes, O. John,Drake, Richard R.,Wang, Binghe
, p. 10338 - 10340 (2011)
Certain carbohydrate-based biomarkers are known to correlate with cancer formation and progression. By targeting sialyl Lewis X, we have developed the first boronolectin-MS tag conjugate, which allows for MALDI-based imaging of cancer based on its cell su
CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING
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Page/Page column 43; 46, (2013/03/26)
Disclosed are conjugates that can bind to one or more site on cancer cell surface, for example, surface proteins, compound specific receptors and carbohydrates that comprise the surface of specific cell types. The disclosed conjugates can thereby serve as