133787-01-6Relevant academic research and scientific papers
Cobalt-Catalyzed Aerobic Oxidative Cleavage of Alkyl Aldehydes: Synthesis of Ketones, Esters, Amides, and α-Ketoamides
Li, Tingting,Hammond, Gerald B.,Xu, Bo
, p. 9737 - 9741 (2021/05/31)
A widely applicable approach was developed to synthesize ketones, esters, amides via the oxidative C?C bond cleavage of readily available alkyl aldehydes. Green and abundant molecular oxygen (O2) was used as the oxidant, and base metals (cobalt and copper) were used as the catalysts. This strategy can be extended to the one-pot synthesis of ketones from primary alcohols and α-ketoamides from aldehydes.
Asymmetric electrochemical oxidation of 1,2-diols, aminoalcohols, and?aminoaldehydes in the presence of chiral copper catalyst
Minato, Daishirou,Arimoto, Hitomi,Nagasue, Yoko,Demizu, Yosuke,Onomura, Osamu
, p. 6675 - 6683 (2008/12/20)
Asymmetric oxidation of 1,2-diols, aminoalcohols, and aminoaldehydes in the presence of copper(II) triflate and (R,R)-Ph-BOX was accomplished by electrochemical method using Br- as a mediator. This oxidation was applicable to kinetic resolution of racemic cis-cycloalkane-1,2-diols, aminoalcohols, and aminoaldehydes to afford optically active compounds with good to high enantioselectivity.
Effecient kinetic resolution of racemic amino aldehydes by oxidation with N-iodosuccinimide
Minato, Daishirou,Nagasue, Yoko,Demizu, Yosuke,Onomura, Osamu
supporting information; experimental part, p. 9458 - 9461 (2009/05/06)
(Chemical Equation Presented) Selective recognition: The first efficient method for the kinetic resolution of racemic amino aldehydes (see scheme, PG=protecting group) is based on a copper(II)/(R,R)-Ph-BOX complex. The coordinated amino aldehydes were tra
