474011-77-3Relevant academic research and scientific papers
Effecient kinetic resolution of racemic amino aldehydes by oxidation with N-iodosuccinimide
Minato, Daishirou,Nagasue, Yoko,Demizu, Yosuke,Onomura, Osamu
scheme or table, p. 9458 - 9461 (2009/05/06)
(Chemical Equation Presented) Selective recognition: The first efficient method for the kinetic resolution of racemic amino aldehydes (see scheme, PG=protecting group) is based on a copper(II)/(R,R)-Ph-BOX complex. The coordinated amino aldehydes were tra
Asymmetric electrochemical oxidation of 1,2-diols, aminoalcohols, and?aminoaldehydes in the presence of chiral copper catalyst
Minato, Daishirou,Arimoto, Hitomi,Nagasue, Yoko,Demizu, Yosuke,Onomura, Osamu
, p. 6675 - 6683 (2008/12/20)
Asymmetric oxidation of 1,2-diols, aminoalcohols, and aminoaldehydes in the presence of copper(II) triflate and (R,R)-Ph-BOX was accomplished by electrochemical method using Br- as a mediator. This oxidation was applicable to kinetic resolution of racemic cis-cycloalkane-1,2-diols, aminoalcohols, and aminoaldehydes to afford optically active compounds with good to high enantioselectivity.
Caspase inhibitors and uses thereof
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, (2008/06/13)
The present invention relates to novel classes of compounds of formula I which are caspase and TNF-alpha inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of th
