1337953-72-6

Basic information

• Product Name: (R)-(-)-1-acetoxy-1-(4-methoxyphenyl)-2-propylene
• Synonyms: (R)-(-)-1-acetoxy-1-(4-methoxyphenyl)-2-propylene
• CAS NO: 1337953-72-6
• Molecular Weight: 206.241
• Mol File: 1337953-72-6.mol

Chemical Properties

• CAS DataBase Reference: (R)-(-)-1-acetoxy-1-(4-methoxyphenyl)-2-propylene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1-acetoxy-1-(4-methoxyphenyl)-2-propylene(1337953-72-6)
• EPA Substance Registry System: (R)-(-)-1-acetoxy-1-(4-methoxyphenyl)-2-propylene(1337953-72-6)

Safety Data

• Hazardous Substances Data: 1337953-72-6(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 51410-44-7 1-(4-methoxylphenyl)-2-propen-1-ol 
• 108-05-4 vinyl acetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 1337953-66-8 (S,E)-2-(3-(4-methoxyphenyl)allyl)-4-methyl-2-phenyloxazol-5(2H)-one 
• 1337953-63-5 (S)-4-((R)-1-(4-methoxyphenyl)allyl)-4-methyl-2-phenyloxazol-5(4H)-one 

Relevant articles and documents

Base-Free Dynamic Kinetic Resolution of Secondary Alcohols with a Ruthenium-Lipase Couple

We report the dynamic kinetic resolution (DKR) of various secondary alcohols by the combination of a ruthenium catalyst and an anionic surfactant-activated lipoprotein lipase. The DKR reactions performed under totally base-free conditions at room temperature provided the products of excellent enantiopurities (91-99% ee or greater) in high yields (92-99%). More importantly, the DKR of α-arylallyl alcohols was achieved for the first time with high yields (87-91%).

Highly efficient kinetic resolution of allylic alcohols with terminal double bond

In this study, the lipase-catalyzed kinetic resolution (Novozyme 435) was employed to prepare chiral allylic alcohols and acetates with terminal double bonds in enantiomeric excesses ranging from 94 to >99 %.

Kinetic resolution of allylic alcohols via stereoselective acylation catalyzed by lipase PS-30

By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic allylic alcohols has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 968. Substituent effect is briefly discussed.