13380-39-7

Basic information

• Product Name: (4R)-1-Methyl-4-propyl-L-proline Methyl Ester
• Synonyms: (4R)-1-Methyl-4-propyl-L-proline Methyl Ester;(trans)-4-Propyl-1-methyl-L-proline Methyl Ester;(2S,4R)-4-Propyl-1-Methylpyrrolidine-2-carboxylic Acid Methyl Ester;(4R)-4-Propyl-hygric Acid Methyl Ester;4-Propyl-hygric Acid Methyl Ester
• CAS NO: 13380-39-7
• Molecular Formula: C₁₀H₁₉NO₂
• Molecular Weight: 185.26336
• Product Categories: Chiral Reagents;Heterocycles;Amino Acids & Derivatives
• Mol File: 13380-39-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: (4R)-1-Methyl-4-propyl-L-proline Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-1-Methyl-4-propyl-L-proline Methyl Ester(13380-39-7)
• EPA Substance Registry System: (4R)-1-Methyl-4-propyl-L-proline Methyl Ester(13380-39-7)

Safety Data

• Hazardous Substances Data: 13380-39-7(Hazardous Substances Data)

Usage

Chemical Properties

Brown Oil

Uses

Proline derivative, and an intermediate in the production of biosynthetic antibiotics.

Upstream product

• 67-56-1 methanol 
• 6734-79-8 1-methyl-trans-4-propyl-L-proline hydrochloride 

Downstream Products

• 1146962-73-3 benzyl 6,8-dideoxy-6-[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-D-erythro-α-D-galacto-octopyranoside 
• 1146962-74-4 2-phenylethyl 6,8-dideoxy-6-[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-D-erythro-α-D-galacto-octopyranoside 
• 1146962-75-5 3-phenylpropyl 6,8-dideoxy-6-[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-D-erythro-α-D-galacto-octopyranoside 
• 1146962-76-6 2-(4-methoxyphenyl)ethyl 6,8-dideoxy-6-[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-D-erythro-α-D-galacto-octopyranoside 
• 1146962-77-7 2-(4-nitrophenyl)ethyl 6,8-dideoxy-6-[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-D-erythro-α-D-galacto-octopyranoside 

Relevant articles and documents

Synthesis of 1,2,3-triazole analogues of lincomycin

In search for new antibiotics we replaced the amide moiety of lincomycin 1 by a 1,2,3-triazole ring. The 1,2,3-triazoles 10a-10k were obtained as single regioisomers by 'click reaction' of azide 5 with the alkyne 9k, derived from propyl hygric acid, and the alkyl, aryl, or cycloalkyl alkynes ribosomes 9a-9j. The new analogues proved inactive towards wild-type and A2058G mutant.