133817-97-7Relevant academic research and scientific papers
Chiral [2.2]paracyclophane-based NAC- and NHC-gold(I) complexes Dedicated to Prof. Hubert Schmidbaur on the occasion of his 80th birthday.
G?ker, Verena,Kohl, Simon Robert,Rominger, Frank,Meyer-Eppler, Georg,Volbach, Lucia,Schnakenburg, Gregor,Lützen, Arne,Hashmi, A. Stephen K.
, p. 45 - 52 (2015)
From enantiomerically pure, planar chiral [2.2]paracyclophane amines a series of nitrogen acyclic carbenegold(I) complexes and nitrogen heterocyclic carbenegold(I) complexes are prepared by a modular template synthesis using isonitriles and amines. These
Hydroxy- and Alkoxycyclizations of Enynes Catalyzed by Platinum(II) Chloride
Munoz, Ma. Paz,Mendez, Maria,Nevado, Cristina,Cardenas, Diego J.,Echavarren, Antonio M.
, p. 2898 - 2902 (2003)
The cyclization of 1-en-6-ynes catalyzed by PtCl2 in the presence of water or alcohols affords five or six-membered ring carbocycles containing hydroxy or alkoxy functional groups in high yields. The alkoxycyclizations can also be performed wit
Gold(I)-catalyzed intramolecular [4+2] cycloadditions of arylalkynes or 1,3-enynes with alkenes: Scope and mechanism
Nieto-Oberhuber, Cristina,Perez-Galan, Patricia,Herrero-Gomez, Elena,Lauterbach, Thorsten,Rodriguez, Cristina,Lopez, Salome,Bour, Christophe,Rosellon, Antonio,Cardenas, Diego J.,Echavarren, Antonio M.
, p. 269 - 279 (2008/09/20)
The cyclizations of enynes substituted at the alkyne gives products of formal [4+2] cyclization with Au(I) catalysts. 1,8-Dien-3-ynes cyclize by a 5-exo-dig pathway to form hydrindanes. 1,6-Enynes with an aryl ring at the alkyne give 2,3,9,9a-tetrahydro-1
(Phenylsulfonyl)allenes as substrates for cycloaddition reactions: Intramolecular cyclizations onto unactivated alkenes
Padwa, Albert,Meske, Michael,Murphree, S. Shaun,Watterson, Scott H.,Ni, Zhijie
, p. 7071 - 7080 (2007/10/02)
The reaction of a series of allyl-substituted bis(phenylsulfonyl)methanes or dimethyl malonates with 2,3-bis(phenylsulfonyl)-1,3-butadiene in the presence of base afforded alkenyl-substituted allenes in good yield. The reaction proceeds by initial attack of the soft carbanion onto the terminal position of the diene, and this is followed by PhSO2- elimination to give the phenylsulfonyl-substituted allene. Themal [2 + 2]-cycloaddition proceeded across the C1-C2 double bond of the allene with completely sterospecificity. Stepwise bonding prefers to occur in a 1,6-exo manner rather than in a 1,7-endo fashion. Substitution at the 7-position of the π-bond causes a crossover in the regioselectivity of the [2 + 2]-cycloaddition process. All products can be rationalized by a mechanism which includes an initial carbon-carbon bond formation involving the central allene carbon to give a diradical intermediate. The product distribution is then determined by the substitution pattern of the alkene and the fate of the diradical intermediate.
Atom Economy. A Simple Pd Catalyzed Addition of Pronucleophiles With Dienes
Trost, Barry M.,Zhi, Lin
, p. 1831 - 1834 (2007/10/02)
Replacing allylic alkylations involving allylic halides, carboxylates, etc. by the simple addition of pronucleophiles to dienes enhances efficiency of use of raw materials and reduces generation of stoichiometric by-products.
Methyl Effects in the Cyclization of γ-Epoxy Bis-Sulfones
Benedetti, Fabio,Berti, Federico,Fabrissin, Silvio,Gianferrara, Teresa,Risaliti, Amerigo
, p. 3530 - 3537 (2007/10/02)
A quantitative study on the effects of methyl and gem-dimethyl groups in the intramolecular ring opening of epoxides by bis-sulfonyl carbanions is reported for the formation of cyclopropanes.Reaction rates are increased by methyl groups on the chain conne
