1338235-73-6Relevant articles and documents
Synthesis of the C19 methyl ether of aspercyclide A via germyl-Stille macrocyclisation and ELISA evaluation of both enantiomers following optical resolution
Carr, James L.,Sejberg, Jimmy J. P.,Saab, Fabienne,Holdom, Mary D.,Davies, Anna M.,White, Andrew J. P.,Leatherbarrow, Robin J.,Beavil, Andrew J.,Sutton, Brian J.,Lindell, Stephen D.,Spivey, Alan C.
, p. 6814 - 6824 (2011/11/14)
Aspercyclide A (1) is a biaryl ether containing 11-membered macrocyclic natural product antagonist of the human IgE-FcεRI protein-protein interaction (PPI); a key interaction in the signal transduction pathway for allergic disorders such as asthma. Herein