1338248-69-3Relevant articles and documents
C-H Activation/Metalation Approaches for the Synthesis of Indolizine Derivatives
Bertallo, Camila R. d. S.,Arroio, Thais R.,Toledo, M?nica F. Z. J.,Sadler, Scott A.,Vessecchi, Ricardo,Steel, Patrick G.,Clososki, Giuliano C.
, p. 5205 - 5213 (2019)
The C–H borylation of indolizines has not previously been reported. In this communication, we describe our preliminary efforts to apply this chemistry to this scaffold and contrast this approach to directed metalation. Through these methodologies, it was possible obtain a library of substituted indolizines functionalized on both the pyridinic and pyrrole rings.
Iron(II)-Based Metalloradical Activation: Switch from Traditional Click Chemistry to Denitrogenative Annulation
Roy, Satyajit,Khatua, Hillol,Das, Sandip Kumar,Chattopadhyay, Buddhadeb
, p. 11439 - 11443 (2019/07/17)
A unique concept for the intermolecular denitrogenative annulation of 1,2,3,4-tetrazoles and alkynes was discovered by using a catalytic amount of Fe(TPP)Cl and Zn dust. The reaction precludes the traditional, more favored click reaction between an organic azide and alkynes, and instead proceeds by an unprecedented metalloradical activation. The method is anticipated to advance access to the construction of important basic nitrogen heterocycles, which will in turn enable discoveries of new drug candidates.
On water direct arylation of imidazo[1,2-a]pyridines with aryl halides
Kalari, Saradhi,Babar, Dattatraya A.,Karale, Uttam B.,Makane, Vitthal B.,Rode, Haridas B.
supporting information, p. 2818 - 2821 (2017/06/27)
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