1338441-53-4Relevant academic research and scientific papers
Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence
Donohoe, Timothy J.,Bower, John F.,Baker, David B.,Basutto, Jose A.,Chan, Louis K. M.,Gallagher, Peter
supporting information; experimental part, p. 10611 - 10613 (2011/11/04)
Heck reactions were performed on α,β-unsaturated-δ- sulfonamido intermediates, derived from cross metathesis, to allow the instalment of substituents at the β position. Subsequent one-pot cyclisation/elimination provides an operationally simple, catalytic and convergent synthesis of 2,4,6-trisubstituted pyridines.
