1338469-64-9Relevant academic research and scientific papers
CBr4 Mediated Oxidative C-N Bond Formation: Applied in the Synthesis of Imidazo[1,2-α]pyridines and Imidazo[1,2-α]pyrimidines
Huo, Congde,Tang, Jing,Xie, Haisheng,Wang, Yajun,Dong, Jie
, p. 1016 - 1019 (2016)
The carbon tetrabromide mediated oxidative carbon-nitrogen bond formation of 2-aminopyridines or 2-aminopyrimidines with β-keto esters or 1,3-diones, leading to a variety of complex imidazo[1,2-α]pyridines or imidazo[1,2-α]pyrimidines, is reported. The re
Design, synthesis, and biological evaluation of novel imidazo[1,2-a]pyridinecarboxamides as potent anti-tuberculosis agents
Onajole, Oluseye K.,Lun, Shichun,Yun, Young Ju,Langue, Damkam Y.,Jaskula-Dybka, Michelle,Flores, Adrian,Frazier, Eriel,Scurry, Ashle C.,Zavala, Ambernice,Arreola, Karen R.,Pierzchalski, Bryce,Ayitou, A. Jean-Luc,Bishai, William R.
, p. 1362 - 1371 (2020/07/13)
Tuberculosis (TB) is a highly infectious disease that has been plaguing the human race for centuries. The emergence of multidrug-resistant strains of TB has been detrimental to the fight against tuberculosis with very few safe therapeutic options availabl
Cu(I)-catalysed oxidative coupling of 2-aminopyridines with β-keto esters: Synthesis of imidazo[1,2-a]pyridine-3-carboxylates
Li, Xiaoqing
, p. 525 - 527 (2012/10/30)
A simple, economical, and environmentally friendly copper-catalysed direct oxidative C-N coupling of 2-aminopyridines with β-keto esters using air as oxidation agent for the creation of imidazo[1,2-a]pyridine-3-carboxylates is demonstrated. Imidazo[1,2-a]pyridine is the basic skeleton for a wide range of biological and pharmacological compounds.
Synthesis of imidazo[1,2-a]pyridines by the bis(acetyloxy)(phenyl)- λ3-iodane-Mediated oxidative coupling of 2-aminopyridines with β-keto esters and 1,3-diones
Wang, Xianpei,Ma, Lijuan,Yu, Wei
supporting information; experimental part, p. 2445 - 2453 (2011/09/15)
Imidazo[1,2-a]pyridine-3-carboxylates can be prepared directly from 2-aminopyridines and β-keto esters by using bis(acetyloxy)(phenyl)- λ3-iodane as an oxidant and boron trifluoride etherate as a catalyst. The amount of catalyst plays a key rol
TBAI-catalyzed oxidative coupling of aminopyridines with β-keto esters and 1,3-diones - Synthesis of imidazo[1,2-a]pyridines
Ma, Lijuan,Wang, Xianpei,Yu, Wei,Han, Bing
supporting information; experimental part, p. 11333 - 11335 (2011/11/29)
TBAI could catalyze the direct oxidative C-N coupling of 2-aminopyridines with β-keto esters and 1,3-diones, which affords imidazo[1,2-a]pyridines as the products. The reaction was realized under metal-free conditions by using tert-butyl hydroperoxide (TB
