133886-45-0Relevant academic research and scientific papers
Stereochemical aspects of intramolecular palladium catalysed [3+2] cycloadditions of methylenecyclopropanes
Corlay, Herve,Motherwell, William B.,Pennell, Andrew M. K.,Shipman, Michael,Slawin, Alexandra M. Z.,Williams, David J.,Binger, Paul,Stepp, Michael
, p. 4883 - 4902 (1996)
The preparation and intramolecular palladium catalysed [3+2] cycloaddition reactions of a range of substrates containing either stereochemically defined 2,3-disubstituted methylenecyclopropanes 3 or acrylate acceptors 12-15 are described. Evidence is presented which supports the hypothesis that these cycloaddition reactions proceed via palladium-trimethylenemethane type intermediates and that the two carbon-carbon bonds are formed in a highly asynchronous manner.
