1338930-83-8

Basic information

• Product Name: 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate
• Synonyms: 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate
• CAS NO: 1338930-83-8
• Molecular Weight: 639.562
• Mol File: 1338930-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate(1338930-83-8)
• EPA Substance Registry System: 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate(1338930-83-8)

Safety Data

• Hazardous Substances Data: 1338930-83-8(Hazardous Substances Data)

Upstream product

• 747392-34-3 1-(2-bromo-5-fluorophenyl)methanamine 
• 309956-78-3 (R)-piperidin-3-ylcarbamic acid tert-butyl ester 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 1338930-86-1 tert-butyl 5-(2-bromo-5-fluorobenzyl)-6-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidine-7-carboxylate 
• 1338930-87-2 tert-butyl-6-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-5-(2-cyano-5-fluorobenzyl)-1,3-dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidine-7-carboxylate 
• 894793-77-2 2-({6-[(3R)-3-amino-piperidin-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl}methyl)-4-fluorobenzonitrile hydrochloride 

Relevant articles and documents

2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3, 4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): A potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivati

We report on the identification of 2-({6-[(3R)-3-amino-3-methylpiperidine- 1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d] pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727) (7a) as a potent and orally active DPP-4 inhibitor withou