1339077-36-9

Upstream product

• 146651-71-0 N-(tert-butyloxycarbonyl)-2-amino-2-(hydroxymethyl)propane-1,3-diol 
• 154627-61-9 5-tert-butoxycarbonylamino-5-hydroxymethyl-2-phenyl-1,3-dioxane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 154627-62-0 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carbaldehyde 

Downstream Products

• 1338833-97-8 C₃₁H₄₅NO₄ 
• 162359-55-9 fingolimod 

Relevant academic research and scientific papers

A convergent synthesis of the immunosuppressant FTY720 employing aqueous Wittig chemistry

A short, convergent synthesis of the immunosuppressant FTY720 is described involving the use of 4-hydroxymethylbenzaldehyde as a pivotal intermediate. A double Wittig strategy was developed to connect this dual-functional aldehyde with an alkyl-tether and to a readily available TRIS-derivative leading to an efficient synthesis of the target molecule.