133910-29-9Relevant academic research and scientific papers
ASYMMETRIC ALDOL REACTION OF SILYL ENOL ETHERS WITH ALDEHYDES PROMOTED BY THE COMBINED USE OF CHIRAL DIAMINE COORDINATED TIN(II) TRIFLATE AND TRIBUTYLTIN FLUORIDE
Kobayashi, Shu,Mukaiyama, Teruaki
, p. 297 - 300 (1989)
Asymmetric aldol reaction of silyl enol ethers of thioesters with aldehydes is performed in high enantiomeric excess by the use of a new chiral promoter, a combined use of chiral diamine coordinated tin(II) triflate and tributyltin fluoride.
Storable, powdered chiral zirconium complex for asymmetric aldol and hetero Diels-Alder reactions
Seki, Kazutaka,Ueno, Masaharu,Kobayashi, Shu
, p. 1347 - 1350 (2008/01/01)
A storable, powdered chiral zirconium catalyst for asymmetric aldol and hetero Diels-Alder reactions has been developed. The catalyst has the same activity as that prepared in situ even after being stored for 3 months. Moreover, this chiral Zr catalyst wo
Highly anti-selective asymmetric aldol reactions using chiral zirconium catalysts. Improvement of activities, structure of the novel zirconium complexes, and effect of a small amount of water for the preparation of the catalysts
Yamashita, Yasuhiro,Ishitani, Haruro,Shimizu, Haruka,Kobayashi, Shu
, p. 3292 - 3302 (2007/10/03)
Catalytic asymmetric aldol reactions of silyl enol ethers with aldehydes (Mukaiyama aldol reactions) have been performed using novel chiral zirconium catalysts. The reactions proceeded in high yields under mild conditions, and anti-adducts were obtained i
The catalytic asymmetric aldol reaction of aldehydes with unsubstituted and monosubstituted silyl ketene acetals: Formation of anti-β-hydroxy-α-methyl esters
Parmee,Hong,Tempkin,Masamune
, p. 1729 - 1732 (2007/10/02)
The title rection with unsubstituted and monosubstituted silyl ketene acetals proceeds with high enantioselectivity, and in the latter case good diastereoselectivity favoring the anti-β-hydroxy-α-methyl esters in all reported cases.
Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System
Kobayashi, Shu,Uchiro, Hiromi,Fujishita, Yuko,Shiina, Isamu,Mukaiyama, Teruaki
, p. 4247 - 4252 (2007/10/02)
In the presence of a chiral promoter consisting of tin(II) triflate, a chiral diamine, and tributyltin fluoride, the silyl enol ether of S-ethyl ethanethioate or S-tert-butyl ethanethioate reacts with aldehydes to afford the corresponding aldol-type adduc
