13398-95-3

Usage

Appearance

White crystalline solid

Solubility

Soluble in water, alcohol, and ether

Uses

a. Photographic developers
b. Hair dyes
c. Rubber antioxidants

Antioxidant

Inhibits oxidation and protects against damage

Skin-lightening

Inhibits melanin production

Skin irritation

Prolonged exposure to high concentrations

Dermatitis

Inflammation of the skin

Potential carcinogenic effects

Linked to cancer development

Regulation

Use is regulated in many countries due to health risks

Safety guidelines

Important to follow when handling and using products containing hydroquinone monoethyl ether

Upstream product

• 107153-33-3 2,5-bis-methoxymethoxy-phenethyl alcohol 
• 2688-48-4 5-Hydroxy-2-coumaranone 
• 7417-19-8 2-(2,5-dimethoxyphenyl)ethanol 
• 87905-74-6 hydroquinone bis(methoxymethyl)ether 
• 123-31-9 hydroquinone 
• 60-12-8 2-phenylethanol 

Downstream Products

• 110450-79-8 1,4-Bis-(tert-butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-benzene 
• 110450-80-1 2-[2,5-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethanol 
• 110450-81-2 [2,5-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-acetaldehyde 
• 108536-24-9 cis-erbstatin 
• 100827-28-9 erbstatin 
• 110450-83-4 N-{(Z)-2-[2,5-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinyl}-formamide 
• 110450-82-3 N-{(E)-2-[2,5-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinyl}-formamide 

Relevant academic research and scientific papers

Lysosome-Targeted Chemotherapeutics: Half-Sandwich Ruthenium(II) Complexes That Are Selectively Toxic to Cancer Cells

Poor selectivity between cancer cells and normal cells is one of the major limitations of cancer chemotherapy. Lysosome-targeted ruthenium-based complexes target tumor cells selectively, only displaying rather weak cytotoxicity or inactivity toward normal cells. Confocal microscopy was employed for the first time to determine the cellular localization of the half-sandwich Ru complex.

TOTAL SYNTHESIS OF ERBSTATIN

The total synthesis of erbstatin in six steps and 38percent overall yield from commercially available lactone 1 is presented.