134004-84-5Relevant academic research and scientific papers
Synthesis of 3-indolylarylmethanamides by samarium triiodide catalyzed Friedel-Crafts amidoalkylation
Mao, Hui,Wang, Xiaoxia,Wang, Wencun,He, Liang,Kong, Lichun,Liu, Junhua
experimental part, p. 2582 - 2588 (2009/04/06)
The amidoalkylation of indoles with N-(α-benzotriazol-1-ylalkyl) amides was smoothly realized with samarium triiodide as a catalyst to give a series of novel 3-indolyl arylmethanamides with good yields and selectivities. Georg Thieme Verlag Stuttgart.
N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids
Katritzky, Alan R.,Pernak, Juliusz,Fan, Wei-Qiang,Saczewski, Franciszek
, p. 4439 - 4443 (2007/10/02)
N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.
