13402-55-6 Usage
General Description
4-Hydroxy-1,3-dihydro-indol-2-one is a chemical compound with the molecular formula C8H7NO2. It is a derivative of indole and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 4-HYDROXY-1,3-DIHYDRO-INDOL-2-ONE has been found to possess antioxidant, anti-inflammatory, and antimicrobial properties, making it a potential candidate for drug development. It is also known to have potential in the field of organic light-emitting diodes (OLEDs) due to its luminescent properties. 4-Hydroxy-1,3-dihydro-indol-2-one has attracted significant research interest due to its versatile applications in various fields including medicine and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 13402-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,0 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13402-55:
(7*1)+(6*3)+(5*4)+(4*0)+(3*2)+(2*5)+(1*5)=66
66 % 10 = 6
So 13402-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO2/c10-7-3-1-2-6-5(7)4-8(11)9-6/h1-3,10H,4H2,(H,9,11)
13402-55-6Relevant articles and documents
Potent oxindole based human β3 adrenergic receptor agonists
Stevens, F. Craig,Bloomquist, William E.,Borel, Anthony G.,Cohen, Marlene L.,Droste, Christine A.,Heiman, Mark L.,Kriauciunas, Aidas,Sall, Daniel J.,Tinsley, Frank C.,Jesudason, Cynthia D.
, p. 6270 - 6273 (2008/09/17)
The synthesis and biological evaluation of a series of oxindole β3 adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety.
Novel substituted 4-aminomethylpiperidines as potent and selective human β3-agonists. Part 1: Aryloxypropanolaminomethylpiperidines
Steffan, Robert J.,Ashwell, Mark A.,Solvibile, William R.,Matelan, Edward,Largis, Elwood,Han, Stella,Tillet, Jeffery,Mulvey, Ruth
, p. 2957 - 2961 (2007/10/03)
The synthesis and SAR of a series of human β3 adrenoreceptor agonists based on a template derived from a common pharmacophore coupled with 4-aminomethylpiperidine is described. Potent and selective agents were identified such as 26 that was in vitro active in CHO cells expressing human β3-AR (EC50=49 nM, IA=1.1), and in vivo active in a transgenic mouse model.
