134040-12-3

Upstream product

• 40911-68-0 (1-pentenyl-2-oxy)trimethylsilane 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 134040-05-4 (R)-2-((R)-2-Acetoxy-2-phenyl-ethyl)-6-methoxy-piperidine-1-carboxylic acid methyl ester 
• 30800-90-9 1-phenyl-2-(piperidin-2-yl)ethan-1-one 
• 134040-04-3 (R)-2-((R)-2-Acetoxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 134040-02-1 (R)-2-((R)-2-Hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 76469-99-3 1-(carbomethoxy)-2-phenacylpiperidine 
• 134107-85-0 (S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 134040-02-1 (S)-2-((S)-2-Hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 134040-05-4 (2S,6R)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-6-methoxy-piperidine-1-carboxylic acid methyl ester 
• 6651-40-7 2-(trimethylsilyloxy)-1-butene 

Downstream Products

• 112462-87-0 (-)-5-hydroxysedamine 
• 153401-05-9 (S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-5-oxo-piperidine-1-carboxylic acid methyl ester 
• 153401-03-7 (2S,5S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-5-hydroxy-piperidine-1-carboxylic acid methyl ester 
• 165674-73-7 (2S,5S)-5-Hydroxy-2-((S)-2-hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 92471-52-8 6-Episedacrine 
• 61550-92-3 (-)-Sedacrine 
• 134040-19-0 (S)-2-[(S)-1-Methyl-6-(2-methyl-[1,3]dioxolan-2-ylmethyl)-1,2,3,6-tetrahydro-pyridin-2-yl]-1-phenyl-ethanol 
• 134085-90-8 (S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-6-methoxy-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 134040-17-8 (S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-6-(2-oxo-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 134040-18-9 (S)-2-((S)-2-Acetoxy-2-phenyl-ethyl)-6-(2-methyl-[1,3]dioxolan-2-ylmethyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 134040-20-3 (R)-2-((R)-2-Hydroxy-2-phenyl-ethyl)-6-methoxy-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 61550-92-3 Episedacrine / Sedacrine 
• 134040-19-0 (R)-2-[(R)-1-Methyl-6-(2-methyl-[1,3]dioxolan-2-ylmethyl)-1,2,3,6-tetrahydro-pyridin-2-yl]-1-phenyl-ethanol 
• 134085-90-8 (R)-2-((R)-2-Acetoxy-2-phenyl-ethyl)-6-methoxy-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of β-hydroxypiperidine alkaloids by anodic oxidation of carbamates and hydroboration

The β-hydroxypiperidine alkaloids (±)-pseudoconhydrine, (±)-N-methylpseudoconhydrine, (-)-5-hydroxysedamine, and (+)-sedacryptine were synthesized. Successive functionalization of the piperidine ring via anodic methoxylation allowed the regio- and stereos

Hydroboration of Enecarbamates and the Synthesis of β-Hydroxypiperidine Alkaloids

The β-hydroxypiperidine alkaloids 5, 6 and 8 were diastereoselectively synthesized using hydroboration of enecarbamates 2b-c as a key step.

Sedum alkaloids XII. Synthesis of the new piperidine alkaloids homosedinone and dihomosedinone

The new piperidine alkaloids homosedinone 2 and dihomosedinone 3, isolated from Sedum acre, have been synthesized from (-)-norsedamine 7 by application of the sequence: anodic methoxylation - elimination - nucleophilic addition.