134052-62-3 Usage
General Description
The chemical "(1R,2S,3S,5S)-3-(4-amino-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester" is a complex compound with a molecular structure consisting of a bicyclic octane ring fused with an azetidine ring. It also contains a carboxylic acid and a methyl ester functional group. The compound features a chiral center and has the potential to exhibit stereoisomerism. The presence of an aminophenyl substituent suggests potential pharmaceutical or pharmacological relevance. The exact properties, uses, and applications of this compound are not specified, but its structural components indicate possible interactions with biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 134052-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,0,5 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134052-62:
(8*1)+(7*3)+(6*4)+(5*0)+(4*5)+(3*2)+(2*6)+(1*2)=93
93 % 10 = 3
So 134052-62-3 is a valid CAS Registry Number.
134052-62-3Relevant articles and documents
Synthesis, ligand binding, QSAR, and CoMFA study of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters
Carroll,Gao,Rahman,Abraham,Parham,Lewin,Boja,Kuhar
, p. 2719 - 2725 (2007/10/02)
A series of 3β-(p-substituted phenyl)tropane-2β-carboxylic acid methyl esters (2) were synthesized and found to possess high affinity for the cocaine binding site in rat striatum. The p-chloro (2c) and p-iodo (2n) compounds, which were the most potent analogues prepared, were found to be 85 and 78 times more potent than (-)-cocaine. The p-bromo (2m) and p-methyl (2d) were also 56 and 60 times more potent than cocaine. QSAR and CoMFA studies were conducted to correlate binding affinity of the cocaine analogues with their structural features. Whereas the QSAR study gave relatively low correlations, the CoMFA study gave a correlation with high predictive value.
