1340541-47-0

Upstream product

• 1259298-28-6 4-methoxyphenyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 1401413-63-5 C₂₂H₂₆Cl₃NO₁₁ 
• 1401413-64-6 C₁₉H₂₅NO₉ 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 1227612-71-6 C₁₉H₂₃N₃O₉ 
• 1227612-89-6 C₁₃H₁₇N₃O₆ 
• 100-52-7 benzaldehyde 
• 14131-63-6 D-glucosamine hydrochloride 
• 122210-05-3 1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose 
• 150-76-5 4-methoxy-phenol 
• 171032-74-9 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose 
• 1139852-98-4 2-(acetoxymethyl)-5-azido-6-(4-methoxyphenoxy)tetrahydro-2H-pyran-3,4-diyl diacetate 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 1401413-68-0 C₂₇H₂₉N₃O₆ 
• 1272755-07-3 C₂₇H₃₁NO₆ 
• 1401413-69-1 C₃₀H₃₂Cl₃NO₈ 
• 1401413-73-7 C₄₄H₅₀Cl₃NO₁₇ 
• 1401413-71-5 C₃₇H₃₈Cl₃NO₈ 
• 1401413-11-3 C₃₈H₃₆Cl₃F₃N₂O₇ 

Relevant academic research and scientific papers

Preparation method, intermediate and application of fucosylated chondroitin sulfate trisaccharide

The invention discloses a synthesizing method of a fucosylated chondroitin sulfate trisaccharide repeat unit. The synthesizing method takes beta-penta-acetyl glucose, D-galactosamine hydrochloride andL-fucose, which are easy to acquire, as raw materials t

Synthesis of trisaccharide repeating unit of fucosylated chondroitin sulfate

We described the chemical synthesis of a sulfated trisaccharide repeating unit of fucosylated chondroitin sulfate (FCS), which has significant anticoagulant activity. Well-functionalized monosaccharides were readily prepared, and highly efficient glycosyl

Anthrax capsule surface carbohydrate antigen-based novel trisaccharide 4-methoxyphenoside compound and preparation method thereof

The invention relates to an anthrax capsule surface carbohydrate antigen-based novel trisaccharide 4-methoxyphenoside compound and a preparation method thereof. The structural formula of the trisaccharide 4-methoxyphenoside compound is shown in the description; and in the formula, R1 is an acetyl group, R2 is a benzyl group, R3 is an acetamido group, and the end position is a p-methylphenoxyl group. The compound can be used for preparing oligosaccharide-like conjugates, can be used for synthesis reaches of anthrax carbohydrate vaccines, has the advantages of concise synthesis route, simplicity in operation, low raw material cost, strong versatility, and good glycosylation reaction stereoselectivity, and is suitable for synthesizing various oligosaccharide compounds.

Phthalic Anhydride-Mediated Direct Glycosylation of Anomeric Hydroxy Arabinofuranose: Synthesis of Repeating Oligoarabinofuranoside and Tetradecasaccharide Arabinan Motif of Mycobacterial Cell Wall

An efficient direct phthalic anhydride-mediated one-pot glycosylation method employing anomeric hydroxy arabinofuranose as glycosyl donor and triflic anhydride as activating agent has been developed. This method afforded the desired di- and oligoarabinofu

An investigation of construction of chondroitin sulfate E (CS-E) repeating unit

A series of the derivatives of chondroitin sulfate E (CS-E) disaccharide repeating unit were prepared by postglycosylation–oxidation strategy. The strategy showed excellent performance in glycosylation both on the reactivity and stereoselectivity. Different protecting methodologies were used for the manipulation of disaccharide building blocks. Substitutes at C-4 of glucosyl donors mildly influenced the glycosylation. The current synthesis afforded a feasible approach for the preparation of CS-E repeating unit.

A robust synthesis of N-glycolyl muramyl dipeptide via azidonitration/reduction

A novel synthetic route leading to N-glycolyl muramyl dipeptide (MDP), a bacterial glycopeptide of particular interest in studies of nucleotide-binding oligomerization domain-containing protein 2 (NOD2), is described. The synthetic strategy hinges on the alkylation of benzylidene-protected glucal with 2-bromopropionic acid and thus circumvents a challenging and non-reproducible SN2 step at the C-3 position of glucosamine derivatives. The subsequent sequence includes an azidonitration and an unusual azide reduction/acylation step via an aza ylide/oxaphospholidine intermediate. This approach generates a protected N-glycolyl MDP that can be either subjected to a one-step global deprotection or differentially deprotected to obtain further derivatives.

Chemical synthesis of the tetrasaccharide repeating unit of the O-antigenic polysaccharide from Plesiomonas shigelloides strain AM36565

Chemical synthesis of the tetrasaccharide repeating unit of the O-antigenic polysaccharide from Plesiomonas shigelloides strain AM36565 is reported. Glycosylations between suitably protected monosaccharide synthons were achieved by the activation of thiog

COMPOUNDS AND METHODS FOR CHEMICAL AND CHEMO-ENZYMATIC SYNTHESIS OF COMPLEX GLYCANS

The present invention provides chemical and chemo-enzymatic methods for the synthesis of a wide array of complex asymmetric multi-antennary glycans.

Synthesis of a tetrasaccharide analog corresponding to the repeating unit of the O-polysaccharide of Salmonella enterica O59: Unexpected stereo outcome in glycosylation

Convergent synthesis of a tetrasaccharide analog corresponding to the repeating unit of the O-polysaccharide of Salmonella enterica O59 is presented. A thioglycoside disaccharide donor was prepared by the glycosylation of two thioglycosides by tuning thei

Synthesis of a unique trisaccharide having an acetal linkage between open-chain and cyclic sugar found in the cell wall of Proteus

The first stereoselective synthesis of a unique trisaccharide containing an open-chain glycosyl cyclic acetal moiety found in the cell wall of Proteus has been successfully achieved. Most of the intermediate steps are high yielding and highly reproducible. The acetal linkage of the open-chain d-galactosamine moiety with an (S)-configuration was formed exclusively.