1341125-08-3Relevant academic research and scientific papers
Silica supported tungstosilicic acid as an efficient and reusable catalyst for the one-pot synthesis of β-acetamido ketones via a four-component condensation reaction
Nasr-Esfahani, Masoud,Montazerozohori, Morteza,Gholampour, Tahere
, p. 3653 - 3657 (2010)
Silica supported tungstosilicic acid has been used as an effective catalyst for a modified Dakin-West one-pot, four- component condensation of an aryl aldehyde, an aryl ketone, acetyl chloride and acetonitrile for the synthesis of β-acet- amido ketones. This catalytic system can act as an active, inexpensive, recoverable and recyclable catalyst. Some advantages of this system are short reaction times, good to excellent yields, easy work up and the ability to be carried out at the large scale reactions.
