1342899-83-5Relevant articles and documents
A novel three-step synthesis of Celecoxib via palladium-catalyzed direct arylation
Gaulier, Steven M.,McKay, Reuben,Swain, Nigel A.
, p. 6000 - 6002 (2011)
A novel three linear step synthesis of Celecoxib was achieved in 33% overall yield via a key regioselective direct C-H arylation reaction between a 1,3-disubstituted pyrazole and an aryl bromide.
Efficient copper-catalyzed cross-coupling of nitrogen nucleophiles with N,N-dibenzyl-4-iodobenzenesulfonamide and its application in the synthesis of Celecoxib intermediate
Yong, Fui-Fong,Azri, Miskal,Darrell Lim, Yong-En,Teo, Yong-Chua
, (2020/11/02)
A practical and efficient strategy has been developed for the cross-coupling of N,N-dibenzyl-4-iodobenzenesulfonamide with nitrogen nucleophiles using 0.5–20 mol% of CuI under ligand-free conditions. A variety of nitrogen nucleophiles including nitrogen h