1343413-00-2

Upstream product

• 327077-87-2 2-(4-formylphenoxy)ethyl 4-methylbenzenesulfonate 
• 22042-73-5 4-(2-hydroxy-ethoxy)-benzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 198480-21-6 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-1H-indole 
• 198481-32-2 bazedoxifene 
• 1343413-04-6 2-(4-bromomethylphenoxy)ethyl 4-methylbenzenesulfonate 
• 198481-33-3 bazedoxifene acetate 

Relevant academic research and scientific papers

Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography

A new series of fluoro-pegylated benzyloxybenzenes were designed, synthesized and evaluated as PET probes for early detection of Aβ plaques. Molecular docking revealed that all of the flexible benzyloxybenzenes inserted themselves into the hydrophobic Val

NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF

A novel process is described for the preparation of pharmaceutically useful compounds such as 1-{4-[2-(azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetic acid commonly known as bazedoxifene acetate of the formula-1 using 2-(4-{[5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1H-indol-1-yl]methyl}phenoxy)ethyl-4-methylbenzenzene-1-sulfonate (formula 2a)