327077-87-2

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 22042-73-5 4-(2-hydroxy-ethoxy)-benzaldehyde 

Downstream Products

• 313497-98-2 C₆₂H₇₂O₈ 
• 1253293-98-9 C₇₅H₉₃N₃O₁₁S 
• 15182-92-0 4-(2-dimethylaminoethoxy)benzaldehyde 
• 198481-33-3 bazedoxifene acetate 
• 1343413-04-6 2-(4-bromomethylphenoxy)ethyl 4-methylbenzenesulfonate 
• 1343413-00-2 2-(4-(hydroxymethyl)phenoxy)ethyl 4-methylbenzenesulfonate 
• 198481-32-2 bazedoxifene 
• 198480-21-6 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-1H-indole 
• 149806-75-7 4-(2-azidoethoxy) benzaldehyde 

Relevant academic research and scientific papers

Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography

A new series of fluoro-pegylated benzyloxybenzenes were designed, synthesized and evaluated as PET probes for early detection of Aβ plaques. Molecular docking revealed that all of the flexible benzyloxybenzenes inserted themselves into the hydrophobic Val

NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF

A novel process is described for the preparation of pharmaceutically useful compounds such as 1-{4-[2-(azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetic acid commonly known as bazedoxifene acetate of the formula-1 using 2-(4-{[5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1H-indol-1-yl]methyl}phenoxy)ethyl-4-methylbenzenzene-1-sulfonate (formula 2a)

Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases

The present invention relates to the use of A1 and/or dual A1/A2b agonists of the formulae (IA) and (IB) for preparing a medicament for treating dyslipidemia, metabolic syndrome and diabetes and dyslipidemia, metabolic syndrome and diabetes in association with hypertension and cardiovascular disorders.

Substituted Phenylaminothiazoles and Use Thereof

The present application relates to novel phenylaminothiazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.

SUBSTITUTED PHENYLAMINOTHIAZOLES AND USE THEREOF

The invention relates to novel phenylaminothiazole derivatives, methods for the production thereof, the use thereof for treating and/or preventing diseases, and the use thereof for producing medicaments used for treating and/or preventing diseases, preferably hypertension and other cardiovascular diseases.