198480-21-6 Usage
Description
1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE is a complex organic compound characterized by an indole core with various substituted benzene rings and an azepane moiety. The molecule features multiple benzyl and benzyloxy groups, along with a methyl substituent, suggesting potential pharmacological or biological activity due to its intricate structure. This makes it a promising candidate for therapeutic applications or as a research tool in the fields of organic chemistry and drug discovery.
Uses
Used in Pharmaceutical Industry:
1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE is used as a potential therapeutic agent for its possible pharmacological or biological activity, which may be harnessed to treat various diseases or conditions.
Used in Organic Chemistry Research:
In the field of organic chemistry, 1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE serves as a research tool to explore the synthesis and reactions of complex organic molecules, potentially leading to the discovery of new compounds with unique properties.
Used in Drug Discovery:
1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE is utilized in drug discovery processes to identify new lead compounds with potential therapeutic effects, contributing to the development of novel medications.
Check Digit Verification of cas no
The CAS Registry Mumber 198480-21-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,4,8 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 198480-21:
(8*1)+(7*9)+(6*8)+(5*4)+(4*8)+(3*0)+(2*2)+(1*1)=176
176 % 10 = 6
So 198480-21-6 is a valid CAS Registry Number.
198480-21-6Relevant articles and documents
PROCESS FOR THE PREPARATION OF BAZEDOXIFENE
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Paragraph 0080, (2020/01/12)
The invention relates to a process for preparation of the compound 3-methyl-5-benzyloxy-2-(4-benzyloxyphenyl)-1H-indole 5, an intermediate for the synthesis of bazedoxifene and bazedoxifene acetate.
Industrial production method for bazedoxifene acetate
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Paragraph 0016; 0023; 0052-0057, (2018/03/25)
The invention discloses an industrial production method for bazedoxifene acetate. The production method comprises the following steps: taking p-hydroxy benzaldehyde as a starting material, substituting with chloracetyl-hexamethyleneimine, reducing with borohydride and chlorinating with a chlorinating agent to obtain a compound 4; reacting the compound 4 with 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole to obtain a compound 5; and carrying out debenzylation to obtain a compound 6, and salifying with acetic acid to obtain a target compound which is the bazedoxifene acetate. The defective workmanship of preparation in the prior art is solved, the used reagent is low in cost and easy to obtain, environmental pollution is small, safety is high, an operation process is simple, and thus, the bazedoxifene acetate is suitable for being produced industrially.
PROCESSES AND INTERMEDIATES FOR PREPARING INDOLE PHARMACEUTICALS
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Page/Page column 25; 28, (2014/12/12)
The invention described herein pertains to processes and intermediates for preparing indole containing pharmaceuticals, particularly to processes and intermediates for preparing selective estrogen receptor modulators, such as bazedoxifene.
