134348-51-9

Basic information

• Product Name: 4-Piperidinone, 1-[(4-fluorophenyl)methyl]-
• CAS NO: 134348-51-9
• Molecular Formula: C12H14FNO
• Molecular Weight: 207.248
• Mol File: 134348-51-9.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 4-Piperidinone, 1-[(4-fluorophenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinone, 1-[(4-fluorophenyl)methyl]-(134348-51-9)
• EPA Substance Registry System: 4-Piperidinone, 1-[(4-fluorophenyl)methyl]-(134348-51-9)

Safety Data

• Hazardous Substances Data: 134348-51-9(Hazardous Substances Data)

Upstream product

• 185942-82-9 8-(4-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]decane 
• 1225545-54-9 C₁₄H₁₆FNO₃ 
• 1225789-29-6 C₁₅H₂₀FNO₄ 
• 140-75-0 para-fluorobenzylamine 
• 292638-85-8 acrylic acid methyl ester 
• 26822-37-7 N,N-dimethyl-4-oxopiperidinium iodide 
• 1445-73-4 1-Methyl-4-piperidone 
• 41979-39-9 4-piperidone hydrochloride 
• 459-46-1 4-Fluorobenzyl bromide 
• 41661-47-6 piperidin-4-one 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 177-11-7 4,4-ethylenedioxy-piperidine 

Downstream Products

• 1350909-75-9 N-(4-fluorobenzyl)-3,5-bis(4-methylbenzylidene)-4-piperidone 
• 1354566-78-1 N-(4-fluorobenzyl)-3,5-bis(4-chlorobenzylidene)-4-piperidone 
• 1266543-31-0 N-(4-fluorobenzyl)-3,5-bis(benzylidene)-4-piperidone 
• 1354566-75-8 N-(4-fluorobenzyl)-3,5-bis(4-methoxybenzylidene)-4-piperidone 
• 1369499-55-7 6-(4-fluorobenzyl)-4-(4-methylphenyl)-8-(4-methylbenzylidene)-3,4,5,7-tetrahydro-1H-pyrido[4,3-d]hydropyrimidine-2-thione 
• 1369499-54-6 4-(4-fluorophenyl)-6-(4-fluorobenzyl)-8-(4-fluorobenzylidene)-3,4,5,7-tetrahydro-1H-pyrido[4,3-d]hydropyrimidine-2-thione 
• 1369499-53-5 6-(4-fluorobenzyl)-8-benzylidene-4-phenyl-3,4,5,7-tetrahydro-1H-pyrido[4,3-d]hydropyrimidine-2-thione 
• 1346451-84-0 5-bromo-1-{[1-(4-fluorobenzyl)-4-hydroxypiperidin-4-yl]-methyl}-pyridin-2(1H)-one 
• 1346452-04-7 N-(4-fluorobenzyl)-1-oxa-6-azaspiro[2,5]-octane 
• 1346451-86-2 1-[(1-benzyl-4-hydroxypiperidin-4-yl)-methyl]-4-methyl-pyridin-2(1H)-one 

Relevant articles and documents

Synthesis and biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1, adenosine receptor

The current study describes the synthesis and biological evaluation of a novel series of 2-amino-3-naphthoylthiophenes, with variable modifications at the 4- and 5-position of the thiophene as well as the naphthoyl ring. Allosteric enhancer activity was m

Synthesis and Evaluation of Anti-inflammatory N-Substituted 3,5-Bis(2-(trifluoromethyl)benzylidene)piperidin-4-ones

A total of 24 N-substituted 3,5-bis(2-(trifluoromethyl)benzylidene)piperidin-4-one derivatives were synthesized via aldol condensation, and their anti-inflammatory activities were evaluated. These compounds were found to have no significant cytotoxicity a

1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof

Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.