1344034-11-2Relevant articles and documents
SIRTUIN ACTIVATORS AND ACTIVATION ASSAYS
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Paragraph 0372-0374, (2013/05/08)
Provided are methods and compositions for detecting a compound that activates a sirtuin deacetylase activity on a fluorescent-free activation substrate in vitro. Further provided are sirtuin modulating compounds of the formulas (I)-(XXI), and related compounds (XXXI), (XXXII), (XXXIII), and (XXXIV), including the fluorescent free-substrate SIRT1 activator compounds of formulas (XL), (XI), (XII), and (XIII).